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Objective To investigate the objective law of complication in endoscopic operation of gynecology Method We retrospectively reviewed and analyzed the complications of endoscopic surgery during the decade occurred in 9 municipal or teaching hospitals and 5 district hospitals in Shanghai Results There were total 10 263 cases of operative laparoscopy and 18 306 cases of hysteroscopy The laparoscopic complication rate was 1 51%(155/ 10 263) and incidence of hysteroscopic complication was 0 09%(16/ 18 306) The major common complications in laparoscopic procedures were bleedings (70/ 10 263, 0 68%), 18 infections (18/ 10 263, 0 18%) and 12 organic injuries (12/ 10 263, 0 12%) The complication rate in laparoscopic surgery made by the inexperienced was six times greater than that by the experienced ( P
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0 05). The correct diagnosis before operation was 0 percent, 63 6% of the patients was diagnosed during operation ( P
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Using ovarian cancer cell lines, we studied relationship between C-erbB2 expression and lysis activity of lymphokine-activated killer cells (LAK) and in vitro regulation by ?-interferon (IFN-?). The results showed that C-erbB2 overexpression was associated with resistance to lysis activity of LAK in ovarian cancer; IFN-? could reduce the overexpression of C-erbB2 and increase lysis activity of LAK on ovarian cancer cells in which C-erbB2 were overexpressed.